Exploring GELITA's Softgel Specialties for Omega-3 Filling Materials

June
13, 2025
5 min

In recent years, the nutraceutical and pharmaceutical sectors have observed a marked increase in the demand for effective and high-quality Omega-3 capsules, underpinned by a growing body of research supporting their numerous health advantages. As an industry leader in specialty gelatin solutions, GELITA is committed to providing a comprehensive portfolio of softgel specialties, expertly engineered to cater to diverse customer needs regarding Omega-3 filling materials. This blog post elucidates the scientific principles behind our innovations, emphasizing quality, stability, and functionality.

DELASOL®: A Paradigm of Oxidation Management

In the realm of Omega-3 encapsulation, DELASOL® emerges as an exemplary solution. Traditionally, enteric capsules have been favored to mitigate the occurrence of undesirable “fishy burps.” However, advancements in oil refinement have addressed this issue, leading to a significant enhancement in the sensory qualities of Omega-3 oils. DELASOL®'s contribution extends beyond palatability; it plays a critical role in oxidation management—a vital factor in maintaining the stability and efficacy of Omega-3 fatty acids throughout their lifecycle.

The encapsulation process employed by DELASOL® effectively minimizes oxidative stress by creating a barrier that protects sensitive oils from exposure to environmental factors, such as light and oxygen. Due to high oxidation in the stomach, up to 80% of omega-3 bioactivity can be lost, making overdosing of standard fish oil capsules necessary. Enteric capsules protect the sensitive fatty acids through the gastric phase, enabling smaller, more efficient dosages - especially valuable during omega-3 shortages. With DELASOL®, softgel producers can create enteric capsules in a one-step process – avoiding additional time and costs – while creating brilliantly clear capsules.

EASYSEAL®: Ensuring leaker-free Krill Oil Capsules

Krill oil, renowned for its concentrated levels of Omega-3 fatty acids, has garnered significant attention; however, due to its surface-activity, krill oil tends to cause leaking softgels in capsule production. Recognizing this vulnerability, GELITA has developed EASYSEAL® technology, specifically designed to enhance the stability of lipophilic compounds prone to leakage.

Scientifically based industrial trials have demonstrated the efficacy of EASYSEAL® in maintaining the integrity of krill oil formulations. EASYSEAL® is a specialized gelatin designed to enhance seam formation during capsule production, effectively minimizing the risk of leakage and lowering processing costs. This results in a more reliable product, more yield, increased production speed, and a more sustainable use of raw materials.

RXL® Portfolio: Functional Crosslinking Solutions

Crosslinking in softgel capsules is a natural, yet avoidable, reaction that reduces the solubility of softgels and thus shortens their shelf life. Self-crosslinking occurs when the gelatin in the softgel shell reacts with itself and is accelerated at high temperatures during storage. External crosslinking occurs when the gelatin in the shell reacts with active ingredients in the fill. Omega-3 fatty acids are polyunsaturated, meaning they have multiple double bonds in their carbon chains. These double bonds are reactive sites where oxidation can occur, leading to the formation of peroxides and other oxidation side products (e.g. aldehydes). Traces of these side products in omega-3 fatty acids can create crosslinking with proteins and can influence sensory perception negatively.

GELITA’s RXL® portfolio comprises four specially designed gelatin products that reduce crosslinking in softgel capsules and are adjustable to fill reactivity. RXL® allows for extended shelf life, enhanced storage stability in all climate zones and long-term stability – even for critical fills.

RAPISOL®: Innovations in Delivery Mechanisms

The RAPISOL® specialty offers unique opportunities for advancing Omega-3 delivery mechanisms. Although the primary focus of RAPISOL® has not historically revolved around Omega-3 applications, its capacity for formulating fast-release capsules is noteworthy. Furthermore, the impending introduction of chewable capsules presents a significant advancement in making Omega-3 supplements more palatable and accessible, particularly for children, consumers with pill-fatigue or to differentiate from existing delivery formats.

This innovative delivery form could significantly enhance how Omega-3 supplements are consumed, catering to those who prefer alternative formats while ensuring that the bioactive components remain bioavailable and effective.

Conclusion

In summary, GELITA's softgel specialties combine scientific understanding with proven functionality in the field of Omega-3 encapsulation. Through robust solutions such as DELASOL®'s oxidation management, EASYSEAL®'s reliable sealing properties, the RXL® Portfolio's crosslinking strategies, and the evolving RAPISOL® delivery mechanisms, GELITA empowers partners in the nutraceutical and pharmaceutical industries to meet the growing demand for Omega-3 capsules while ensuring optimal quality and efficacy. Our commitment to research and development continues to fuel the advancement of these technologies, ultimately contributing to improved delivery systems through superior product formulations.

If you want to learn more about GELITA's Softgel Specialties for Omega-3 Filling Materials, download our free eBooks:

https://www.gelita.com/en/blog/ebook/eliminate-crosslinking-rxlr-superior-softgel-shelf-life-and-stability

https://www.gelita.com/en/blog/ebook/softgel-capsules-and-strategies-prevent-omega-3-oil-oxidation

Category: #AmazingGelatin