GELITA offers a comprehensive portfolio of gelatins that provides a broad release profile in soft capsules. Beside a variety of versatile and tailor-made standard gelatins, there are GELITA® RXL and GELITA® RXL Advanced for improved capsule shelf-life and stability. These special gelatins provide reliable release and reduced cross-linking properties, even under extreme storage conditions. Now the GELITA capsule gelatin portfolio is complemented by GELITA® RXL R² for revolutionary fill release. The soft capsules produced with GELITA® RXL R² offer faster release of the fill and offer the added advantage of the reduced cross-linking
properties of the RXL technology.

delivery system release


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The capsule that protects itself: the patented GELITA® RXL technology prevents crosslinking in soft gelatine capsules and thus increases shelf-life. Gelatine capsules are among the most popular dosage forms for drugs, OTC products and food supplements. However, certain types of reactive fillings may cause the gelatine in the capsule to react and crosslink. This is especially true under high temperature and humidity storage conditions. This leads to a lower solubility of the capsules, resulting in longer dissolution times in the gastrointestinal tract.  

To prevent crosslinking, GELITA has introduced a new line of pharmaceutical gelatine that significantly reduces the inter-molecular crosslinking of large gelatine molecules. GELITA® RXL is available from multiple manufacturing sites all around the world and can be sourced from a variety of raw materials.

As the graphs show, the different GELITA® RXL gelatinetypes provide excellent performance for all viscosity levels.After 6 respectively 12 months storage at 40 °C/75 % r.h.the fill release of soft capsules, comprising GELITA® RXL andGELITA® RXL Advanced gelatines, is improved compared tofresh standard gelatine capsules. The GELITA® RXL Advancedgelatines show better performance than the correspondingGELITA® RXL products and all RXL gelatines have much betterfill release than the standard gelatine capsules, producedand stored under the same conditions.

  Release Time RXL Capsule 1


Release Time RXL Capsule 3




The unique Release Profile Portfolio from GELITA enables soft capsule manufacturers to define the timing of the fill release as well as where in the body the capsule should open. Do you want to know more?


Gelatine Capsules


(R squared) Gelatine has been proven in independent capsule experiments to release fills significantly faster than standard gelatine capsules. Consumers may now benefit from the more immediate release of medications, such as sleep aids, allergy treatments, pain relievers and psychological aids. And, the capsule industry itself can likewise benefit from more advanced product differentiation with a stable capsule delivery system that is already widely preferred by consumers. Capsules featuring these advanced releasing properties can promote improved patient compliance for dosage forms that are simple and reliable to manufacture. 

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Is a novel solution for enteric soft-capsules and is the first commercially available gelatine product of its kind – allowing for the one-step production of enteric capsules that open in the intestine (instead of the stomach, as with traditional gelatine capsules). Most enteric delivery systems are produced by applying an acid-insoluble coating to fresh soft capsules. This intensive two-step process adds time and money to the cost of each enteric capsule. With GELITA® EC, capsules producers can manufacture enteric capsules using existing equipment in a one-step process – avoiding additional time and costs – while creating brilliantly clear capsules. GELITA® EC allows manufacturers to produce enteric capsules that adhere to USP (United States Pharmacopeia) dissolution parameters. 

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