GELITA offers a comprehensive portfolio of gelatins that provides a broad release profile in soft capsules. Beside a variety of versatile and tailor-made standard gelatins, there are GELITA® RXL and GELITA® RXL Advanced for improved capsule shelf-life and stability. These special gelatins provide reliable release and reduced cross-linking properties, even under extreme storage conditions. Now the GELITA capsule gelatin portfolio is complemented by GELITA® RXL R² for revolutionary fill release. The soft capsules produced with GELITA® RXL R² offer faster release of the fill and offer the added advantage of the reduced cross-linking
properties of the RXL technology.
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The capsule that protects itself: the patented GELITA® RXL technology prevents crosslinking in soft gelatine capsules and thus increases shelf-life. Gelatine capsules are among the most popular dosage forms for drugs, OTC products and food supplements. However, certain types of reactive fillings may cause the gelatine in the capsule to react and crosslink. This is especially true under high temperature and humidity storage conditions. This leads to a lower solubility of the capsules, resulting in longer dissolution times in the gastrointestinal tract.
To prevent crosslinking, GELITA has introduced a new line of pharmaceutical gelatine that significantly reduces the inter-molecular crosslinking of large gelatine molecules. GELITA® RXL is available from multiple manufacturing sites all around the world and can be sourced from a variety of raw materials.
As the graphs show, the different GELITA® RXL gelatinetypes provide excellent performance for all viscosity levels.After 6 respectively 12 months storage at 40 °C/75 % r.h.the fill release of soft capsules, comprising GELITA® RXL andGELITA® RXL Advanced gelatines, is improved compared tofresh standard gelatine capsules. The GELITA® RXL Advancedgelatines show better performance than the correspondingGELITA® RXL products and all RXL gelatines have much betterfill release than the standard gelatine capsules, producedand stored under the same conditions.