Use the natural power of collagen – with VERISOL®
Collagen is the major structural component of skin, comprising about 80 % of its dry weight. Skin properties are known to be affected by endogenous and environmental factors including aging, ultraviolet radiation, hormones and nutrition. VERISOL® can stimulate skin metabolism and counteract the loss of collagenous extracellular matrix from the inside. Consumers who ingest the natural Bioactive Collagen Peptides® VERISOL® specially optimized for beauty applications can experience noticeably firmer and smoother skin with fewer wrinkles. The positive effect of VERISOL® also shows in an improved skin surface structure, reducing cellulite and a faster nail growth with reportedly less chipping of fingernails.
Orally applied, VERISOL® systematically effects the collagen metabolism in the dermis rather than just reaching the outer layers of the skin like creams and other topical products do.
Mode of Action
The specific peptides of VERISOL® are recognized by the fibroblast cells in the dermal layer of the skin as collagen fragments like those resulting from catabolic activities. Therefore they are stimulated to increase their collagen metabolism to counter-balance the pretended collagen degradation in the dermis. The result is a considerably higher production of dermal collagen and overall extracellular matrix, replacing what is lost through aging and environmental influences.
Collagen synthesis in vitro
Significant improvement of skin health
VERISOL® consists of special collagen peptides – important components for supporting healthy skin. Administered orally,
VERISOL® influences the skin’s collagen metabolism directly from the inside. It increases the skin moisture and delays the formation of wrinkles. Several scientific experiments investigated the potential of VERISOL®.
Higher skin elasticity1
The first study with 69 women aged between 35 and 55 years revealed that VERISOL® leads to significantly higher skin elasticity – up to 15 % – compared to placebo treatment. This effect could be measured after just 4 weeks of treatment and persisted after 8 weeks of oral VERISOL® administration. Another 4 weeks after the last intake of the product, VERISOL® application still showed higher skin elasticity levels than in the placebo treated group.
Skin elasticity increased significantly afteroral VERISOL® treatment in comparison to placebo administration.
1 Oral Supplementation of Specific Collagen Peptides Has Beneficial Effects on Human Skin Physiology: A Double-Blind, Placebo-Controlled Study
Proksch E., Segger D., Degwert J., Schunck M., Zague V., Oesser S. Skin Pharmacol Physiology, August 2013
Reduction of wrinkles2
The second study with more than 100 women aged between 45 and 65 years shows that the oral administration of VERISOL® (2.5 g/day) significantly reduces wrinkles after 4 weeks and leads to a significantly higher skin procollagen concentration.
VERISOL® significantly reduces wrinkles: The collagen in the skin increases by 60%.
2 Oral Intake of Specific Bioactive Collagen Peptides Reduces Skin Wrinkles and Increases Dermal Matrix Synthesis
Proksch E., Schunck M., Zague V., Segger D., Degwert J., Oesser S. Skin Pharmacol Physiology, December 2013
Improved skin surface structure and decrease of cellulite
About 85 % of the global female adult population is affected by cellulite (the orange peel appearance of skin). Cellulite is a beauty aspect, not a disease, but many women suffer from this beauty flaw. Cellulite is mainly caused by dermal matrix disturbances, in combination with excess of subcutaneous fat, bulging into the dermis as well as excess of intersistal fluid.
VERISOL® supplementation has beneficial effects on the dermal extracellular matrix of the skin and can help to decrease cellulite. Contrary to current cellulite supplements that mainly address the aspects of excessive fat or microcirculation/drainage, VERISOL® directly stimulates the extracellular matrix formation in skin.
Density of dermis (ultrasound measurement)
Significant decrease of wavines
Significant higher dermal density after 6 month
Significant decrease of cellulite score3
A double blind, randomized, placebo controlled study with 105 women aged between 25 and 50 years shows that the daily oral intake of 2.5 g VERISOL® significantly decreases the cellulite score. The effect was measured after 3 and 6 months supplementation. VERISOL® has a beneficial effect on skin extracellular matrix and restores the normal structure of the dermis and subcutaneous tissue. VERISOL® supplementation also reduced the waviness of the skin, with first results visible after 3 months, but more pronounced after 6 months. With a daily dose of 2.5 g VERISOL® the appearance of cellulite women with a BMI < 25 was significantly reduced.
As part of the study, changes in the dermal density were investigated. The two ultrasound scans show side by side the skin of a participant in the placebo group compared to the skin of a participant from the VERISOL® group. The increase in elastin and collagen is clearly visible.
3 JOURNAL OF MEDICINAL FOOD, J Med Food 00 (0) 2015, 1–9, DOI: 10.1089/jmf.2015.0022, Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology
Michael Schunck, 1 Vivian Zague, 2 Steffen Oesser, 1 Ehrhardt Proksch, 3
Promoting growth and health of fingernails4
For many women, well-groomed fingernails are an inseparable part of an attractive appearance. But many women suffer from cracked or chipped nails as well as nail peeling and nail roughness. The Bioactive Collagen Peptides® VERISOL® can help to improve growth and health of fingernails.