Vaccine Stabilization

Safeguarding Efficacy

The efficacy of vaccines depends not only on their active components but also on their stability. To ensure this, stabilizing agents are used—most commonly gelatin or its hydrolysate—due to their proven compatibility, safety, and functionality in vaccine formulations.

Gelatin as a Proven Stabilizer in Modern Vaccines

Vaccines are among the medical profession’s most effective tools. They help to prevent and reduce the impact of numerous infectious diseases, including hepatitis, whooping cough, shingles, flu and Covid-19. But their effectiveness relies heavily on their stability.

For this reason, vaccines contain stabilizing agents to protect their active ingredients. The stabilizer has to fulfil numerous requirements: It has to be non-allergenic. It must be compatible with the vaccine’s active ingredients and easy to handle in the manufacturing process. As it satisfies all of these requirements and more, gelatine or its hydrolysate is commonly used as a vaccine stabilizer.

VACCIPRO® – The Gold Standard

Our gold standard vaccine stabilizer VACCIPRO® is made from gelatin-derived specialized collagen peptides. VACCIPRO® is able to protect the fragile ingredients in vaccines against environmental stresses such as temperature fluctuation and agitation during packaging and transport. It also has benefits for shelf life, so vaccines last longer in storage. Thus, it enhances vaccine stability, safeguarding their safety and effectiveness.

 

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Protection Against Mechanical Stress

Many active components in vaccines, such as proteins or antigens, are sensitive to mechanical stress like stirring or shaking. Mechanical forces can cause these molecules to alter their structure or even break down. 

If the molecular structure changes, this can reduce the effectiveness of vaccines or even render them completely inactive. 

Gelatin acts as a protective agent by forming a stabilizing matrix, reducing the movement of the molecules and protecting them from mechanical forces. Additionally, gelatin helps maintain the structural integrity of the molecules, ensuring that they retain their function even under temperature or movement stress. 

In this way, gelatin helps preserve the effectiveness of vaccines during transport and storage.

Key Benefits

Ensures Efficacy

helps maintain the potency of vaccines, ensuring they remain effective until they are administered

Extends Shelf Life

prolongs vaccine shelf life, reducing the need for frequent batch manufacturing. Disposal of unused vaccines is less frequent

Enhances Safety

low allergenicity reduces the risk of adverse reactions in patients

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VACCIPRO®

The Gold Standard in Vaccine Stabilization

VACCIPRO® collagen peptides provide exceptional compatibility and performance as a stabilizer in injectable formulations, effectively protecting and increasing the stability of vaccines.

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VACCIPRO®: The Gold Standard in Vaccine Stabilisation