Addressing Stability Challenges in Softgel Production
Evolving market demands and the rise of nutraceuticals such as botanicals, with reactive ingredients like polyphenols, aldehydes and ketones, have created stability challenges for softgel manufacturers. These ingredients have a tendency to crosslink with gelatin softgel shells. Additional factors, such as storage, temperature and humidity, can exacerbate and accelerate crosslinking too. For its RXL® portfolio, GELITA uses patented technologies to significantly reduce gelatin’s ability to interact with reactive molecules, resulting in reliable softgel capsules of superior quality.
Why RXL®?
- Exceptional anti-crosslinking properties, adaptable to fill reactivity
- Improved storage stability across all ICH climatic zones, including hot and humid conditions
- Reliable fill release throughout and beyond the product’s shelf life
- Suitable for Rx, Gx, OTC and dietary supplement applications
- Longer shelf life than standard gelatin softgels
- Long-lasting stability for challenging fills such as botanicals
- Minimized pellicle formation
- Available in various gelatin types
RXL® Ultra: The New Gold Standard
RXL® Ultra is GELITA’s latest innovation, designed to eliminate crosslinking in softgels by covalently bonding succinic acid to the free amino groups in gelatin. RXL® Ultra retains all the benefits of traditional gelatin while solving extreme crosslinking challenges, ensuring more reliable products for consumers. Approved for pharmaceutical use in the EU, RXL® Ultra is already used in more than 50 OTC products.
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Portfolio
In addition to the comprehensive RXL® range, GELITA offers tailor-made gelatins for different release profiles. For instance, softgels made with RAPISOL® offer revolutionary rapid fill release in less than five minutes, while DELASOL® is the first gelatin product on the market to enable production of enteric capsules in just one simple step. Last but not least, EASYSEAL® completes GELITA’s softgel specialties portfolio. With its unique properties, EASYSEAL® increases seam thickness, reducing leakage during softgel production and significantly.
