FORTIGEL® – keeps joints fit and mobile.
FORTIGEL® – Keeping people physically active and mobile
Today, every fourth person suffers from joint problems. And the number is constantly increasing. The principal reason is wear and tear of the joint cartilage brought about by age and mechanical stress. But help is available for sufferers. With FORTIGEL®, GELITA has developed an innovative ingredient for the regeneration of joint cartilage. The protein collagen makes up some 70% of cartilage mass. The optimized specific collagen peptides of FORTIGEL® have been proven to stimulate the growth of new cartilage by stimulating cells helping to relieve joint pain and make the joints smooth and mobile. Thus, products containing FORTIGEL® can improve quality of life.
FORTIGEL® promotes growth of cartilage tissue
The effect of FORTIGEL® has been scientifically proven in numerous studies. According to published research, orally administered FORTIGEL® has been shown to be absorbed intestinally and to accumulate in cartilage. The ingestion of FORTIGEL® stimulates a statistically significant increase of cartilage tissue metabolism.
Penn State study confirms improvement of mobility with FORTIGEL®
At Penn State University (USA, 2008), 147 athletes were recruited who had all complained of activity-related joint pain. Those athletes (mean age 20.1 years) were subdivided into one group taking FORTIGEL® as a nutritional supplement and a control group taking a placebo for 24 weeks. The severity of symptoms was rated both by the treating physician and by the study participants themselves with a visual analogue scale.
As this was also a prospective, randomized, placebo-controlled double-blind study, it was interesting to see that in some important parameters relating to the perception of pain, there was a statistically significant difference between treatment and the control group. As far as alternative therapies were concerned, like hydrotherapy, massages and ice and heat packs, there was also a clear-cut difference between the treatment and the placebo group in favor of the FORTIGEL® group. This was the first trial to show improvement of joint pain in athletes who were treated with FORTIGEL®.
In summary, the studies confirm that the consumption of FORTIGEL® results in relief of symptoms and improvement of mobility in healthy individuals.
McAlindon proves long term effect of FORTIGEL®
The most recent study published in March 2011 by McAlindon and colleagues investigated the long term effect of FORTIGEL® treatment on the composition of hyaline cartilage in individuals with early knee osteoarthritis. This prospective, randomized, double-blind, placebo-controlled pilot study was performed at the Tufts Medical Center in cooperation with Harvard University.
For the investigation, a specific type of magnetic resonance imaging (dGEMRIC) was used in order to visualize structural changes in the cartilage tissue of the respective study participants. Overall, 30 patients were randomized into one group receiving 10g FORTIGEL® a day for 48 weeks and a control group obtaining a placebo. Three magnetic resonance imaging scans of the knee were performed on each subject, one at baseline, one at 24 weeks and the final scan at 48 weeks.
The analysis of the cartilage scans revealed a statistically significant increase of proteoglycan density in the medial and lateral tibial regions of the FORTIGEL®-treated patients compared to the placebo group. The results indicate that oral supplementation of FORTIGEL® has a direct impact on human cartilage tissue. This confirms previous experimental data and clearly demonstrates that specific orally administered collagen peptides can have an influence on cartilage tissue turnover. It can be assumed that this observed effect is not limited to pathophysiological conditions, as indicated by additional clinical studies, and thus can also be efficacious in healthy cartilage maintaining normal joint function.
Interview with Dr. Klaus Flechsenhar from Sanofi-Aventis Deutschland GmbH about FORTIGEL®
FORTIGEL® preserves quality of life
Based on the presented data it can be concluded that the oral administration of FORTIGEL® has a beneficial effect on cartilage tissue. Consequently, supplementation of FORTIGEL® peptides can contribute to the maintenance of joint health and could help to preserve mobility and quality of life.
FORTIGEL® is a natural protein of neutral odor and taste that can be easily integrated into many applications. It provides excellent solubility and delivers clear solutions without interacting with other ingredients.
Make innovative product ideas a reality!
FORTIGEL® can enhance the most diverse of foodstuffs, including dairy products, functional food, dietary supplements and drinks.
• Natural food
• Clean label (no E numbers)
• Highly digestible food
• Non-allergenic food